Development of predictive equations for total body water using the deuterium-dilution method as the gold standard in a population of asymptomatic HIV-positive Zulu women in South Africa
Keywords: HIV, women, total body water (TBW), lean body mass (LBM), anthropometry, predictive equation, bio-electrical impedance analysis (BIA), Deuterium enrichment, FTIR
AbstractObjectives: The study aimed to derive predictive equations for total body water determinations with bioelectrical impedance and anthropometric measurements in a population of asymptomatic human immunodeficiency virus (HIV) -positive Zulu women. Design: Cross-sectional data from within an ongoing prospective study that observed the effect of infant feeding mode on maternal and child health in a cohort of asymptomatic HIV-positive women were used for this objective. Setting: A community health centre in Durban. Subjects: Asymptomatic HIV-infected women who were not eligible for antiretroviral therapy. They were resident in the area and were of Zulu ethnicity. Outcome measures: Development of predictive equations for total body water. Results: Success was achieved in developing predictive equations for total body water using bioelectrical impedance analysis and anthropometric measurements that were specific to the HIV-positive female Zulu population. These equations were developed using the total body water that was obtained from deuterium-dilution method as a gold standard. Conclusion: These predictive equations are likely to be more valid for the HIV-positive female African populations of similar build than the current predictive equations that derive from the Western population.
How to Cite
Kindra, G., Coutsoudis, A., Pillay, L., & Kindness, A. (2012). Development of predictive equations for total body water using the deuterium-dilution method as the gold standard in a population of asymptomatic HIV-positive Zulu women in South Africa. South African Journal of Clinical Nutrition, 25(4), 186-191. Retrieved from http://sajcn.redbricklibrary.com/index.php/SAJCN/article/view/618
Material submitted for publication in the South African Journal of Clinical Nutrition (SAJCN) is accepted provided it has not been published elsewhere. Copyright forms will be sent with acknowledgement of receipt and the SAJCN reserves copyright of the material published.
The SAJCN does not hold itself responsible for statements made by the authors.