The Gastrointestinal Tract and HIV Pathogenesis

  • Jane Helen Downs King Edward VIII Hospital
Keywords: Gastrointestinal Tract, HIV Pathogenesis

Abstract

Gastrointestinal dysfunction has been recognized as a major manifestation of the human immunodeficiency virus (HIV) infection usually presenting as diarrhoea which may or may not be due to the presence of an opportunistic infection of the GIT. Contrary to earlier assumptions, there is now substantial evidence to demonstrate that there are significant changes in the gut in the acute phase of HIV infection. The most significant of these being the substantial loss of the CD4+ T-cells in the GIT. Delays in the initiation of HAART (that is, once the CD4+ T-cell count drops below 200 cells/uL), is associated with a greater severity of HIV-associated GIT enteropathy, and poor clinical outcome.

Author Biography

Jane Helen Downs, King Edward VIII Hospital
Dept of Dietetics King Edward VIII Hospital KwaZulu-Natal
How to Cite
Downs, J. (1). The Gastrointestinal Tract and HIV Pathogenesis. South African Journal of Clinical Nutrition, 23(2), S65-S68. Retrieved from http://sajcn.redbricklibrary.com/index.php/SAJCN/article/view/407
Section
Invited Communications